Not known Details About https://www.ceesdekker.net
Not known Details About https://www.ceesdekker.net
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Spatial structure facilitates cooperation in a social dilemma: empirical proof from the bacterial Group
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Deposition and atomic power microscopy of person phthalocyanine polymers between nanofabricated electrodes
2010, made a brand new way (‘wedging transfer’) to manipulate nanostructures; very first report of DNA translocation by way of graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into solid-state nanopores
SMC complexes can move Bodily roadblocks bigger than their ring size, indicating a nontopological system for DNA loop extrusion
‘At first we looked at Organic units having a Bodily watch and acted on The premise from the equipment we understood. It took a number of years prior to we commenced Performing more on the big biological troubles. I then began to connect with it nanobiology, a term that did not exist at time.
2011, initially in vitro measurements of transportation throughout just one biomimetic nuclear pore sophisticated; improvement of multiplexed magnetic tweezers for kilo-molecule experiments; and resolved the system of homology recognition in DNA homologous recombination
2003, shown the 1st biosensors manufactured from a carbon nanotube; settled the structure and mechanism of DNA maintenance proteins; and discovery of a completely new procedure for fabricating reliable-condition nanopores for DNA translocation
Dekker started out his research on one carbon nanotubes in 1993 when he create a brand new line of investigate to review electrical transport by solitary organic molecules concerning nanoelectrodes. In 1996 a breakthrough was recognized with carbon nanotubes. This was achieved in a very collaboration With all the team of Nobel laureate Richard Smalley. STM and nanolithography tactics were accustomed to show that these nanotubes are quantum wires at The one-molecule level, with remarkable physical Houses.
Because 2000 he moved to one-molecule biophysics and nanobiology, with investigation from research of DNA loop extrusion and supercoiling to DNA translocation as a result of nanopores. A lot more lately his exploration has focused on finding out chromatin structure and mobile division with bacteria on chip, though he can be attempting to eventually build synthetic cells from The underside up.
Cees Dekker is Distinguished College Professor at TU Delft. Experienced to be a physicist, he pioneered nanotechnology with lots of discoveries on carbon nanotubes during the nineteen nineties. Considering the fact that 2000, he moved to one-molecule biophysics and nanobiology. His latest exploration focuses on (i) nanopores for protein sequencing; (ii) chromosome construction, particularly SMC motor protein; and (iii) building a living artificial mobile from lifeless molecules. Dekker is undoubtedly an elected member in the KNAW and fellow for cees dekker the APS as well as the IOP.
2008, initially observation of protein-coated DNA translocation by nanopores; solved the origin on the electrophoretic pressure on DNA in nanopores; uncovered a major velocity boost of microtubules in electric fields; found an anomalous electro-hydrodynamic orientation of microtubules; and resolved the origin of sounds in carbon nanotubes in liquid
Example (two) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is proven in gray, the rim in the pore is highlighted in red, plus a 3D rendering of the motion of the DNA rod is shown.